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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2025; 31(30): 110145
Published online Aug 14, 2025. doi: 10.3748/wjg.v31.i30.110145
Published online Aug 14, 2025. doi: 10.3748/wjg.v31.i30.110145
Clinical efficacy and mechanism of Bletilla striata and Chinese herbal compounds in treatment of peptic ulcer
Yi-Tong Sun, Fang Zhou, The First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China
Hong-Xin Zheng, School of Basic Medical Sciences, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China
Jing-Dong Xiao, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China
Co-corresponding authors: Hong-Xin Zheng and Jing-Dong Xiao.
Author contributions: Sun YT and Zhou F drafted the manuscript; Zheng HX and Xiao JD revised and approved the final version of the article, and both authors contribute equally to this study as co-corresponding authors.
Supported by National Science and Technology Major Project, No. 2024ZD0521002; The Innovation Team Project of Traditional Chinese Medicine of Liaoning Province, No. LNZYYCXTD-CCCX-003; General Program of the National Natural Science Foundation of China, No. 82074296; and Construction Project of Inheritance Studios of Famous Chinese Medicine Experts in China, No. [2022] No. 75.
Conflict-of-interest statement: Authors declare that they have no competing interests.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Xin Zheng, PhD, Professor, School of Basic Medical Sciences, Liaoning University of Traditional Chinese Medicine, No. 79 Chongshan East Road, Shenyang 110032, Liaoning Province, China. zhenghx2002@126.com
Received: June 5, 2025
Revised: July 3, 2025
Accepted: July 14, 2025
Published online: August 14, 2025
Processing time: 62 Days and 22.9 Hours
Revised: July 3, 2025
Accepted: July 14, 2025
Published online: August 14, 2025
Processing time: 62 Days and 22.9 Hours
Core Tip
Core Tip: Bletilla striata has shown notable effects in the treatment of peptic ulcers. Clinical studies indicate that it can not only alleviate ulcer symptoms but also promote ulcer healing and enhance patients’ quality of life. The mechanisms of action of Bletilla striata and its traditional Chinese medicine compound formulations require further investigation and are believed to involve multiple processes, including anti-inflammatory activity, antioxidant effects, and promotion of gastric mucosal repair.