Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2025; 31(2): 98031
Published online Jan 14, 2025. doi: 10.3748/wjg.v31.i2.98031
Imaging characteristics of hypervascular focal nodular hyperplasia-like lesions in patients with chronic alcoholic liver disease
Atsushi Urase, Masakatsu Tsurusaki, Ryohei Kozuki, Atsushi Kono, Keitaro Sofue, Kazunari Ishii
Atsushi Urase, Masakatsu Tsurusaki, Ryohei Kozuki, Atsushi Kono, Kazunari Ishii, Department of Radiology, Kindai University, Faculty of Medicine, Osakasayama 589-8511, Osaka, Japan
Masakatsu Tsurusaki, Department of Radiology, Kansai Medical University Medical Center, Moriguchi 570-8507, Osaka, Japan
Keitaro Sofue, Department of Radiology, Kobe University Graduate School of Medicine, Kobe 650-0017, Hyogo, Japan
Author contributions: Urase A, Tsurusaki M, Sofue K, Kozuki R, Kono A, Ishii K wrote the paper; Urase A and Tsurusaki M designed research; Tsurusaki M performed research; Urase A, Tsurusaki M, Sofue K, Kozuki R, Kono A contributed new reagents or analytic tools; Tsurusaki M analyzed data.
Institutional review board statement: This retrospective study was performed with the approval of the institutional ethics committee of Kindai University, Faculty of Medicine.
Informed consent statement: Informed consent for using their computed tomography and magnetic resonance images and biopsy specimens was obtained from all patients.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: Raw data used in this study are available from the corresponding author upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Masakatsu Tsurusaki, MD, PhD, Professor, Department of Radiology, Kindai University, Faculty of Medicine, 377-2 Ohnohigashi, Osakasayama 589-8511, Osaka, Japan. mtsuru@dk2.so-net.ne.jp
Received: June 15, 2024
Revised: October 25, 2024
Accepted: November 18, 2024
Published online: January 14, 2025
Processing time: 185 Days and 16.2 Hours
Core Tip

Core Tip: Two enhancement patterns were observed for the hepatobiliary phase on gadoxetic acid-enhanced magnetic resonance imaging (MRI): Heterogeneous hyperintense (43%) and ring-like enhancement (57%), and all lesions exhibited a marked homogeneous uptake pattern on superparamagnetic iron oxide-enhanced MRI in patients with focal nodular hyperplasia-like lesions. This finding is of clinical relevance because it is useful for the differential diagnosis of hypervascular liver nodules in patients with chronic liver disease.