Prognostic value of the triglyceride-glucose index in gastric cancer

doi:10.3748/wjg.v31.i17.104651

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May 7, 2025 (publication date) through Apr 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Gastroenterol. May 7, 2025; 31(17): 104651
Published online May 7, 2025. doi: 10.3748/wjg.v31.i17.104651

Prognostic value of the triglyceride-glucose index in gastric cancer

Tugce Eskazan, Suat Saribas, Bekir Kocazeybek

Tugce Eskazan, Department of Internal Medicine, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul 34640, Türkiye

Suat Saribas, Bekir Kocazeybek, Department of Medical Microbiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul 34098, Türkiye

Co-first authors: Tugce Eskazan and Suat Saribas.

Author contributions: Eskazan T and Saribas S contribute equally to this study as co-first authors; Eskazan T, Saribas S, and Kocazeybek B contributed to this paper; Kocazeybek B designed the overall concept; Eskazan T contributed to the writing, discussion and design of the manuscript; Saribas S contributed to the editing the manuscript, illustrations, and review of literature.

Conflict-of-interest statement: There is no conflict of interest related to this letter to the editor.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Bekir Kocazeybek, Professor, Department of Medical Microbiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Kocamustafapaşa St No. 53, Istanbul 34098, Türkiye. bzeybek@istanbul.edu.tr

Received: December 27, 2024
Revised: March 4, 2025
Accepted: March 21, 2025
Published online: May 7, 2025
Processing time: 123 Days and 21.2 Hours

Core Tip

Core Tip: Gastric cancer (GC) remains a high-mortality malignancy despite advances in diagnostics and treatments. Histopathological and biochemical markers that predict prognosis are crucial for treatment planning and assessing mortality and morbidity risk. Recent studies highlight the prognostic value of the triglyceride-glucose ratio (an indirect indicator of insulin resistance) in various cancer types. However, a deeper understanding of its role in predicting the immunotherapy response in GC is critically needed.