Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2025; 31(17): 103156
Published online May 7, 2025. doi: 10.3748/wjg.v31.i17.103156
Vonoprazan and proton pump inhibitors: Which is superior for Helicobacter pylori eradication?
Mubin Ozercan, Ahmed Tawheed, Alaa Ismail, Mohab Sherif Amer, Mohamed El-Kassas
Mubin Ozercan, Department of Gastroenterology, Firat University, Elazig 23119, Türkiye
Ahmed Tawheed, Mohamed El-Kassas, Department of Endemic Medicine, Helwan University, Cairo 11795, Egypt
Alaa Ismail, Mohab Sherif Amer, Faculty of Medicine, Helwan University, Cairo 11795, Egypt
Co-corresponding authors: Ahmed Tawheed and Mohamed El-Kassas.
Author contributions: El-Kassas M designed the overall concept and outline of the manuscript; Ozercan M and Tawheed A wrote the manuscript; Ismail A and Amer MS searched the literature. El-Kassas M and Tawheed A are co-corresponding authors for this article, and both made equal contributions. All authors contributed to this article and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohamed El-Kassas, Department of Endemic Medicine, Helwan University, Ain Helwan, Cairo 11795, Egypt. m_elkassas@hq.helwan.edu.eg
Received: November 11, 2024
Revised: February 16, 2025
Accepted: March 12, 2025
Published online: May 7, 2025
Processing time: 170 Days and 0.9 Hours
Core Tip

Core Tip: In this article, we summarize the current evidence regarding the better choice between proton pump inhibitors and vonoprazan for treating the very common global disease Helicobacter pylori infection. We also comment on a recently published article by Gao et al, where the authors provided real-life experiences managing Helicobacter pylori in the elderly using vonoprazan.