Shi PN, Song ZZ, He XN, Hong JM. Evaluation of scoring systems and hematological parameters in the severity stratification of early-phase acute pancreatitis. World J Gastroenterol 2025; 31(15): 105236 [DOI: 10.3748/wjg.v31.i15.105236]
Corresponding Author of This Article
Jie-Ming Hong, MD, Chief Physician, Department of Gastroenterology, Ningbo Yinzhou No. 2 Hospital, No. 998 Qianhe North Road, Yinzhou District, Ningbo 315000, Zhejiang Province, China. jm_hong@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Clinical Trials Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Apr 21, 2025; 31(15): 105236 Published online Apr 21, 2025. doi: 10.3748/wjg.v31.i15.105236
Evaluation of scoring systems and hematological parameters in the severity stratification of early-phase acute pancreatitis
Pei-Na Shi, Zhang-Zhang Song, Xu-Ni He, Jie-Ming Hong
Pei-Na Shi, Zhang-Zhang Song, Xu-Ni He, Jie-Ming Hong, Department of Gastroenterology, Ningbo Yinzhou No. 2 Hospital, Ningbo 315000, Zhejiang Province, China
Author contributions: Shi PN and Hong JM designed the research; Song ZZ and He XN contributed to the data collection; Shi PN and He XN analyzed the data; Shi PN, Song ZZ, and Hong JM wrote the paper. All authors reviewed the manuscript.
Institutional review board statement: The study was approved by the Human Ethics Committee of the Yinzhou No. 2 Hospital (approval number: Y2024-50).
Clinical trial registration statement: This clinical trial was registered at ClinicalTrials.gov, No. ChiCTR2500098956.
Informed consent statement: Informed consent statement has been applied for exemption for this study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie-Ming Hong, MD, Chief Physician, Department of Gastroenterology, Ningbo Yinzhou No. 2 Hospital, No. 998 Qianhe North Road, Yinzhou District, Ningbo 315000, Zhejiang Province, China. jm_hong@126.com
Received: January 18, 2025 Revised: February 24, 2025 Accepted: March 25, 2025 Published online: April 21, 2025 Processing time: 92 Days and 4.6 Hours
Core Tip
Core Tip: Acute pancreatitis (AP) is an emergency gastrointestinal disease that requires immediate diagnosis and urgent clinical treatment. An accurate assessment and staging of severity are essential in initial intensive therapy. This study systematically explored the prognostic value of inflammatory markers and several scoring systems in severity stratification of early-phase AP. 463 patients with AP were enrolled in this study. The results revealed that C-reactive protein measured within 48 hours, calcium and prognostic nutritional index measured within 48 hours were independent risk factors for predicting severe AP. Computed tomography severity index, bedside index of severity in AP, and the combination of prognostic nutritional index measured within 48 hours and the Ranson score can act as reliable predictor of severity AP.
