Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 14, 2025; 31(14): 103921
Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103921
Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103921
Using vaporized hydrogen peroxide for anhydrous disinfection of gastrointestinal endoscopes
Can Zhao, Chinese PLA Medical School, Beijing 100853, China
Can Zhao, Long-Song Li, Ying-Ying Wang, Ning-Li Chai, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
Li-Hong Qi, Ting Liang, Institute of NBC Defence PLA Army, Beijing 102205, China
Co-corresponding authors: Ting Liang and Ning-Li Chai.
Author contributions: Chai NL and Zhao C designed the study; Zhao C and Qi LH conducted the research; Liang T provided the experimental equipment and location; Wang Y offered software and hardware support; Zhao C analyzed the data and wrote the manuscript; Chai N and Li LS jointly reviewed the paper; All authors have read and approved the final manuscript. Chai NL and Liang T are co-corresponding authors. Chai NL applied for and obtained the funding for this research project. Liang T, an outstanding expert in the field of disinfection, provided reliable technical support for this study. The collaboration between Chai NL and Liang T is crucial for the publication of this manuscript and the ongoing progress of the project.
Supported by the Joint Logistics Support Force Comprehensive Equipment Research Project, No. LB2023B010100-09.
Institutional review board statement: This study did not involve human subjects, hence no ethical approval was obtained.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: All original data from the experiments can be obtained by contacting the authors at chainingli@vip.163.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning-Li Chai, MD, Chief Physician, Professor, Department of Gastro
Received: December 5, 2024
Revised: February 22, 2025
Accepted: March 17, 2025
Published online: April 14, 2025
Processing time: 127 Days and 21 Hours
Revised: February 22, 2025
Accepted: March 17, 2025
Published online: April 14, 2025
Processing time: 127 Days and 21 Hours
Core Tip
Core Tip: This study pioneers an anhydrous disinfection method for gastrointestinal endoscopes using vaporized hydrogen peroxide generated from sodium percarbonate granules. Demonstrating comparable efficacy to traditional liquid disinfectants, the method achieves high-level disinfection within 30 minutes while reducing water use, costs (1.5 China Yuan per cycle), and environmental impact. Key factors-humidity, exposure dosage, and organic burden-significantly influence efficacy, with no adverse effects from flow rate variations. This innovation aligns with green endoscopy goals, offering a sustainable, efficient alternative to resource-intensive reprocessing, and sets a foundation for future anhydrous sterilization technologies.