Unveiling the intricacies: Insight into gastroesophageal reflux disease

doi:10.3748/wjg.v31.i1.98479

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Jan 7, 2025 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2025; 31(1): 98479
Published online Jan 7, 2025. doi: 10.3748/wjg.v31.i1.98479

Unveiling the intricacies: Insight into gastroesophageal reflux disease

Nilanka Wickramasinghe, Niranga Manjuri Devanarayana

Nilanka Wickramasinghe, Department of Physiology, Faculty of Medicine, University of Colombo, Colombo 00800, Western Province, Sri Lanka

Niranga Manjuri Devanarayana, Department of Physiology, Faculty of Medicine, University of Kelaniya, Ragama 11010, Western Province, Sri Lanka

Author contributions: Wickramasinghe N and Devanarayana NM wrote the main manuscript text and prepared figures and tables.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Niranga Manjuri Devanarayana, MBBS, MD, PhD, Professor, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama 11010, Western Province, Sri Lanka. niranga@kln.ac.lk

Received: June 27, 2024
Revised: October 26, 2024
Accepted: November 11, 2024
Published online: January 7, 2025
Processing time: 165 Days and 6.8 Hours

Core Tip

Core Tip: To enhance physicians' understanding of gastroesophageal reflux disease (GERD), it is crucial to comprehensively examine its risk factors, underlying pathophysiological mechanisms, current diagnostic modalities, and diverse management strategies tailored to various patient profiles. Additionally, identifying the determinants contributing to treatment failures is essential. By delving into these aspects, healthcare providers can better address GERD, a significant global health challenge.