Nabi Z, Inavolu P, Duvvuru NR. Prediction, prevention and management of gastroesophageal reflux after per-oral endoscopic myotomy: An update. World J Gastroenterol 2024; 30(9): 1096-1107 [PMID: 38577183 DOI: 10.3748/wjg.v30.i9.1096]
Corresponding Author of This Article
Zaheer Nabi, FASGE, MBBS, MD, Consultant Physician-Scientist, Department of Gastroenterology, Asian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad 500082, Telangana, India. zaheernabi1978@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Zaheer Nabi, Pradev Inavolu, Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, Telangana, India
Nageshwar Reddy Duvvuru, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangana, India
Author contributions: Nabi Z and Inavolu P wrote the manuscript; Duvvuru NR provided critical inputs to the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zaheer Nabi, FASGE, MBBS, MD, Consultant Physician-Scientist, Department of Gastroenterology, Asian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad 500082, Telangana, India. zaheernabi1978@gmail.com
Received: December 17, 2023 Peer-review started: December 17, 2023 First decision: January 16, 2024 Revised: January 26, 2024 Accepted: February 18, 2024 Article in press: February 18, 2024 Published online: March 7, 2024 Processing time: 79 Days and 9.6 Hours
Core Tip
Core Tip: Per-oral endoscopic myotomy (POEM) has gained recognition as a primary therapeutic intervention for achalasia cardia. POEM is distinguished by its effectiveness and a commendable safety profile. However, gastroesophageal reflux disease (GERD) has emerged as an important long term adverse event after POEM. Notably, the incidence of GERD is higher after POEM when compared to the other leading treatment modalities including pneumatic dilatation and Heller’s myotomy with fundoplication. Since the introduction of POEM in 2010, there has been considerable advancement in our understanding of GERD after POEM. This article aims to elucidate the recent developments in predicting, preventing, assessing, and managing GERD subsequent to POEM intervention.
