Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2024; 30(46): 4929-4936
Published online Dec 14, 2024. doi: 10.3748/wjg.v30.i46.4929
Emphysematous pancreatitis: Diagnosis, treatment, and prognosis
Li-Jun Cao, Zhong-Hua Lu, Pin-Jie Zhang, Xiang Yang, Wei-Li Yu, Yun Sun
Li-Jun Cao, Zhong-Hua Lu, Pin-Jie Zhang, Xiang Yang, Wei-Li Yu, Yun Sun, The First Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Co-first authors: Li-Jun Cao and Zhong-Hua Lu.
Author contributions: Cao LJ and Lu ZH contributed equally to this study, designing the research and overseeing data collection; Zhang PJ was responsible for data analysis and interpretation; Yang X participated in the patient management and provided clinical insights; Yu WL contributed to the molecular and genetic studies; Sun Y, as the corresponding author, supervised the entire study process, coordinated among the different departments, and was involved in writing and revising the manuscript; All authors reviewed and approved the final manuscript.
Supported by Clinical Research Cultivation Program at The Second Affiliated Hospital of Anhui Medical University, No. 2021LCYB12; The Support Program for Elite Young Talents in Colleges and Universities of Anhui Province, No. gxyq2022006; The National Natural Science Foundation Incubation Program of The Second Affiliated Hospital of Anhui Medical University, No. 2022GMFY09 and No. 2022GMFY10; The Provincial Quality Engineering Project of Higher Education Institutions of Anhui Province, No. 2022jyxm750; and Natural Science Research Project of Colleges and Universities of Anhui Province, No. 2023AH053168, No. 2024AH050800 and No. 2024AH040107.
Institutional review board statement: The study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of the Second Affiliated Hospital of Anhui Medical University (Approval No. YX2023-136).
Informed consent statement: Written informed consent was obtained from all participants involved in the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Data supporting the results of this study are available from the corresponding author upon reasonable request at sunyun9653@126.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun Sun, MD, Chief Physician, The First Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei 230601, Anhui Province, China. sunyun9653@126.com
Received: September 9, 2024
Revised: September 27, 2024
Accepted: October 29, 2024
Published online: December 14, 2024
Processing time: 72 Days and 20.9 Hours
Core Tip

Core Tip: Emphysematous pancreatitis (EP) is a rare and severe condition with high mortality. This study highlights the role of next-generation sequencing in improving pathogen identification and emphasizes early percutaneous drainage, aggressive antimicrobial therapy, and minimally invasive interventions. Delayed surgery, when necessary, may improve outcomes, especially in early-onset and common-type EP patients.