Effects and mechanisms of Helicobacter pylori infection on the occurrence of extra-gastric tumors

doi:10.3748/wjg.v30.i37.4090

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 30, Issue 37

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (1848)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-1) series.

Item

Count

PDF

HTML

1268

Figures (1-1)

Tables (1-1)

159

Sum=1527

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=158

Publishing Process of This Article

Item

Count

Browse

Download

Sum=106

Oct 7, 2024 (publication date) through Nov 20, 2024

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. Oct 7, 2024; 30(37): 4090-4103
Published online Oct 7, 2024. doi: 10.3748/wjg.v30.i37.4090

Effects and mechanisms of Helicobacter pylori infection on the occurrence of extra-gastric tumors

Shi-Qing Zhao, Hui-Ling Zheng, Xiao-Tian Zhong, Zi-Ye Wang, Yi Su, Yan-Yan Shi

Shi-Qing Zhao, Xiao-Tian Zhong, Zi-Ye Wang, Yi Su, Yan-Yan Shi, Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 100191, China

Shi-Qing Zhao, Xiao-Tian Zhong, Zi-Ye Wang, Yi Su, Health Science Center, Peking University, Beijing 100191, China

Hui-Ling Zheng, Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China

Co-first authors: Shi-Qing Zhao and Hui-Ling Zheng.

Author contributions: Zhao SQ and Zheng HL contributed to drafting the manuscript and making charts; Shi YY was responsible for designing and revising this review; Zhong XT, Wang ZY, and Su Y provided suggestions and contributed to discussion; All authors have read and approved the article.

Supported by Beijing Natural Science Foundation, No. J230002.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/

Corresponding author: Yan-Yan Shi, MD, Professor, Research Center of Clinical Epidemiology, Peking University Third Hospital, No. 49 Garden North Road, Haidian District, Beijing 100191, China. shiyanyan@bjmu.edu.cn

Received: April 9, 2024
Revised: August 23, 2024
Accepted: September 12, 2024
Published online: October 7, 2024
Processing time: 170 Days and 7.2 Hours

Core Tip

Core Tip: Apart from gastric diseases, several studies have revealed an association between Helicobacter pylori (H. pylori) and extra-gastric diseases, including cancers. Inflammation, systemic immune responses, microbiome disorders, and hypergastrinemia caused by H. pylori may change the tumor microenvironment and eventually contribute to extra-gastric carcinogenesis. However, the research in this field remains controversial. We summarized the effects of H. pylori infection on the occurrence of extra-gastric tumors and their possible mechanisms, hoping to provide insights for clinical treatment and management of H. pylori-related extra-gastric tumors, as well as help improve prognosis.