Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2024; 30(34): 3883-3893
Published online Sep 14, 2024. doi: 10.3748/wjg.v30.i34.3883
Clinical features of gastroesophageal reflux disease and erosive esophagitis: Insights from patients undergoing esophagogastroduodenoscopy in resource-limited Ethiopia
Firehiwot A Mengistie, Abate B Shewaye, Abel T Tasamma, Zekarias S Ayalew
Firehiwot A Mengistie, Abate B Shewaye, Abel T Tasamma, Zekarias S Ayalew, Department of Internal Medicine, Addis Ababa University, Addis Ababa 1176, Addis Ababa, Ethiopia
Firehiwot A Mengistie, Department of Internal Medicine, Rheum Rheumatology and Internal Medicine Specialty Clinic, Addis Ababa 1000, Addis Ababa, Ethiopia
Abate B Shewaye, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Adera Medical and Surgical Center, Addis Ababa 1000, Addis Ababa, Ethiopia
Co-corresponding authors: Firehiwot A Mengistie and Zekarias S Ayalew.
Author contributions: Mengistie FA and Ayalew ZS contribute equally to this study as co-corresponding authors. Mengistie FA and Shewaye AB contribute to the conceptualization, methodology, investigation, analysis, and writing of the manuscript; Tasamma AT and Ayalew ZS contribute to the methodology, data curation, drafting, interpretation, and edition of the data and supervision, supervision, and edition of the manuscript.
Institutional review board statement: The ethical clearance of the study was obtained from the Institutional Review Board of Addis Ababa University, College of Health Sciences.
Informed consent statement: Consent forms have been acquired from all participants.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The dataset is available from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Firehiwot A Mengistie, MD, Chief Physician, Department of Internal Medicine, Addis Ababa University, Churchill St., Addis Ababa 1176, Addis Ababa, Ethiopia. firehiwotabebe671@gmail.com
Received: May 22, 2024
Revised: August 24, 2024
Accepted: August 30, 2024
Published online: September 14, 2024
Processing time: 110 Days and 12.4 Hours
Core Tip

Core Tip: This multicenter study in a resource-limited setting identified risk factors for severe erosive esophagitis (EE) in patients with gastroesophageal reflux disease (GERD) undergoing esophagogastroduodenoscopy. Age 50 years or above, bleeding, and duodenitis/duodenopathy were associated with worse EE. These findings can inform risk stratification for patients with GERD in similar settings.