Isakov V. Autoimmune gastritis studies and gastric cancer: True renaissance or bibliometric illusion. World J Gastroenterol 2024; 30(32): 3783-3790 [PMID: 39221066 DOI: 10.3748/wjg.v30.i32.3783]
Corresponding Author of This Article
Vasily Isakov, AGAF, MD, PhD, Chief, Professor, Department of Gastroenterology and Hepatology, Federal Research Center of Nutrition, Biotechnology and Food Safety, 21 Kashirskoye Shosse, Moscow 115446, Russia. vasily.isakov@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 28, 2024; 30(32): 3783-3790 Published online Aug 28, 2024. doi: 10.3748/wjg.v30.i32.3783
Autoimmune gastritis studies and gastric cancer: True renaissance or bibliometric illusion
Vasily Isakov
Vasily Isakov, Department of Gastroenterology and Hepatology, Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow 115446, Russia
Author contributions: Isakov V contributed to the writing, and editing the manuscript, and review of literature.
Supported byMinistry of Science and High Education of Russia, No. FGMF-2022-0005.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Vasily Isakov, AGAF, MD, PhD, Chief, Professor, Department of Gastroenterology and Hepatology, Federal Research Center of Nutrition, Biotechnology and Food Safety, 21 Kashirskoye Shosse, Moscow 115446, Russia. vasily.isakov@gmail.com
Received: June 8, 2024 Revised: August 8, 2024 Accepted: August 13, 2024 Published online: August 28, 2024 Processing time: 79 Days and 18.5 Hours
Core Tip
Core Tip: Autoimmune gastritis (AIG) is associated with a lower risk of gastric cancer than expected due to the low prevalence of precancerous lesions. In contrast, the risk of type 1 neuroendocrine tumors (Type1-NETs) is high and always co-exists with anti-parietal cell antibodies and extensive oxyntic atrophy. Endoscopic surveillance is needed for the early diagnosis and curative treatment of Type1-NETs. The progression of gastric atrophy during the course of AIG leads to hypochlorhydria and subsequent changes in the gastric microbiome. Among the numerous species harboring the stomach in patients with atrophic AIG, Streptococcus anginosus is one of the key candidates to be a driver of gastric carcinogenesis in post- Helicobacter pylori era.
