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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2024; 30(32): 3755-3765
Published online Aug 28, 2024. doi: 10.3748/wjg.v30.i32.3755
Published online Aug 28, 2024. doi: 10.3748/wjg.v30.i32.3755
Primary hyperparathyroidism-induced acute pancreatitis in pregnancy: A systematic review with a diagnostic-treatment algorithm
Goran Augustin, Department of Surgery, University Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb 10000, Croatia
Quirino Lai, General Surgery and Organ Transplantation Unit, Department of Surgery, Sapienza University of Rome, Rome 00018, Italy
Maja Cigrovski Berkovic, Department for Sport and Exercise Medicine, Faculty of Kinesiology, University of Zagreb, Zagreb 10000, Croatia
Author contributions: Augustin G and Cigrovski Berkovic M contributed to supervision of the research, and manuscript drafting and writing; Augustin G, Lai Q, and Cigrovski Berkovic M contributed to the data collection; Augustin G and Lai Q contributed to the data analyses; Lai Q contributed to the statistical analyses.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Goran Augustin, MD, Associate Professor, Department of Surgery, University Hospital Centre Zagreb and School of Medicine University of Zagreb, Kišpatićeva 12, Zagreb 10000, Croatia. augustin.goran@gmail.com
Received: January 19, 2024
Revised: July 11, 2024
Accepted: August 2, 2024
Published online: August 28, 2024
Processing time: 220 Days and 17.1 Hours
Revised: July 11, 2024
Accepted: August 2, 2024
Published online: August 28, 2024
Processing time: 220 Days and 17.1 Hours
Core Tip
Core Tip: Primary hyperparathyroidism (PHPT)-induced acute pancreatitis (AP) in pregnancy is extremely rare. Definitive diagnosis of PHPT-induced AP in pregnancy is delayed if serum calcium is not tested during admission. PHPT-induced AP starts at the 20th gestational week. Maternal and fetal mortality was 9.3%. Maternal mortality was higher with higher serum lipase levels and earlier delivery week. Higher calcium and PTH values increased fetal/child mortality, abortions, and complex deliveries Early diagnosis and immediate intervention lead to excellent maternal and fetal outcomes.