Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2024; 30(26): 3253-3256
Published online Jul 14, 2024. doi: 10.3748/wjg.v30.i26.3253
Mean nocturnal baseline impedance in gastro-esophageal reflux disease diagnosis: Should we strictly follow the Lyon 2 Consensus?
Theodoros A Voulgaris, Georgios P Karamanolis
Theodoros A Voulgaris, Georgios P Karamanolis, Department of Gastroenterology, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece
Co-first authors: Theodoros A Voulgaris and Georgios P Karamanolis.
Author contributions: Voulgaris TA and Karamanolis GP contributed equally to manuscript preparation. Voulgaris TA and Karamanolis GP contributed equally to this work as co-first authors.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Theodoros A Voulgaris, MD, PhD, Researcher, Department of Gastroenterology, School of Medicine, National and Kapodistrian University of Athens, Agiou Thoma 17, Athens 11527, Greece. thvoulgaris87@gmail.com
Received: April 14, 2024
Revised: May 27, 2024
Accepted: June 13, 2024
Published online: July 14, 2024
Processing time: 86 Days and 6.2 Hours
Core Tip

Core Tip: Mean nocturnal baseline impedance (MNBI) values add significant strength to a pH-impedance study, can help the clinician identify the correct explanation for a patient’s symptoms and tailor the patient’s therapy. Specific MNBI cut-offs have been proposed by several studies for characterizing patients with reflux symptoms. However, caution should be taken before applying the proposed cut-offs by the Lyon 2 Consensus as patient age, body mass index and origin may affect MNBI values.