Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2024; 30(17): 2369-2370
Published online May 7, 2024. doi: 10.3748/wjg.v30.i17.2369
Targeting therapy for hepatocellular carcinoma by delivering microRNAs as exosomal cargo
Takeshi Suda
Takeshi Suda, Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minami Uonuma 949-7302, Niigata, Japan
Author contributions: Suda T read the review article by Wang et al and wrote this entire letter to the editor.
Conflict-of-interest statement: The author declares he has no conflicts of interest in relation to this letter.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Takeshi Suda, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, 4132 Urasa, Minami Uonuma 949-7302, Niigata, Japan. tspitt@med.niigata-u.ac.jp
Received: January 20, 2024
Revised: March 6, 2024
Accepted: April 11, 2024
Published online: May 7, 2024
Processing time: 106 Days and 3.2 Hours
Core Tip

Core Tip: Wang et al thoroughly explored the functions and biomedical significance of exosomal microRNAs transferred by both parenchymal and nonparenchymal cells in the framework of potential therapeutic targets for hepatocellular carcinoma. This review aimed to do more than just summarize the role of microRNAs in hepatocarcinogenesis. It also sought to illuminate the process of cellular communication using exosomal microRNA cargo. Therefore, it would be beneficial for the review to include information on how this cargo is delivered to target cells.