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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2024; 30(15): 2096-2108
Published online Apr 21, 2024. doi: 10.3748/wjg.v30.i15.2096
Published online Apr 21, 2024. doi: 10.3748/wjg.v30.i15.2096
Probiotics: Shaping the gut immunological responses
Eirini Filidou, Leonidas Kandilogiannakis, George Kolios, Faculty of Medicine, Laboratory of Pharmacology, Democritus University of Thrace, Alexandroupolis 68100, Greece
Anne Shrewsbury, Katerina Kotzampassi, Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki 54636, Greece
Author contributions: Filidou E, Kandilogiannakis L, Shrewsbury A, Kolios G and Kotzampassi K contributed to this paper; Filidou E, Kolios G and Kotzampassi K designed the overall concept and outline of the manuscript; Kotzampassi K contributed to the discussion and design of the manuscript; Filidou E and Kandilogiannakis L contributed to the writing, and editing the manuscript, illustrations, and review of literature; Shrewsbury A contributed to the writing and the linguistic editing of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Katerina Kotzampassi, MD, PhD, Senior Scientist, Surgeon, Department of Surgery, Aristotle University of Thessaloniki, St Kiriakidi 1, Thessaloniki 54636, Greece. kakothe@yahoo.com
Received: January 24, 2024
Peer-review started: January 24, 2024
First decision: February 8, 2024
Revised: February 28, 2024
Accepted: March 28, 2024
Article in press: March 28, 2024
Published online: April 21, 2024
Processing time: 85 Days and 12.9 Hours
Peer-review started: January 24, 2024
First decision: February 8, 2024
Revised: February 28, 2024
Accepted: March 28, 2024
Article in press: March 28, 2024
Published online: April 21, 2024
Processing time: 85 Days and 12.9 Hours
Core Tip
Core Tip: Probiotics, such as Lactiplantibacillus plantarum and Saccharomyces cerevisiae, exert remarkable anti-inflammatory properties on the gut's immune responses. These beneficial microorganisms not only restore immunity markers but also enrich the gut's microbiota, crucial for a healthy microbial balance. Incorporating probiotics or foods rich in these beneficial microorganisms, particularly in conditions such as inflammatory bowel disease, holds promise for restoring gut health, boosting the immune system, and alleviating inflammation.