Risk factors for lymph node metastasis in superficial esophageal squamous cell carcinoma

doi:10.3748/wjg.v30.i13.1810

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Apr 7, 2024 (publication date) through May 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2024; 30(13): 1810-1814
Published online Apr 7, 2024. doi: 10.3748/wjg.v30.i13.1810

Risk factors for lymph node metastasis in superficial esophageal squamous cell carcinoma

Yan-Bo Yu

Yan-Bo Yu, Department of Gastroenterology, Laboratory of Translational Gastroenterology, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China

Author contributions: Yu YB designed the overall concept and outline of the manuscript and contributed to the writing, and editing the manuscript.

Conflict-of-interest statement: The authors declare no conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Yan-Bo Yu, MD, PhD, Professor, Doctor, Department of Gastroenterology, Laboratory of Translational Gastroenterology, Qilu Hospital, Shandong University, No. 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China. yuyanbo2000@126.com

Received: January 6, 2024
Peer-review started: January 6, 2024
First decision: January 16, 2024
Revised: February 1, 2024
Accepted: March 13, 2024
Article in press: March 13, 2024
Published online: April 7, 2024

Core Tip

Core Tip: Endoscopic resection is a routine treatment for superficial esophageal squamous cell carcinoma, but the risk of lymph node metastasis (LNM) limits its application to some extent. Tumor size, invasion depth, tumor differentiation, tumor infiltrative growth pattern, tumor budding, and lymphovascular invasion were shown to be significantly correlated with LNM.