Strum WB, Boland CR. Advances in acute and chronic pancreatitis. World J Gastroenterol 2023; 29(7): 1194-1201 [PMID: 36926670 DOI: 10.3748/wjg.v29.i7.1194]
Corresponding Author of This Article
Williamson B Strum, MD, Research Scientist, Department of Gastroenterology, Scripps Clinic, No. 10666 N Torrey Pines Road, La Jolla, CA 92037, United States. williamsonstrum@yahoo.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Feb 21, 2023; 29(7): 1194-1201 Published online Feb 21, 2023. doi: 10.3748/wjg.v29.i7.1194
Advances in acute and chronic pancreatitis
Williamson B Strum, Clement Richard Boland
Williamson B Strum, Department of Gastroenterology, Scripps Clinic, La Jolla, CA 92037, United States
Clement Richard Boland, Department of Medicine, University of California San Diego, La Jolla, CA 92037, United States
Author contributions: Strum WB and Boland CR were equal contributors to the manuscript.
Conflict-of-interest statement: There are no conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Williamson B Strum, MD, Research Scientist, Department of Gastroenterology, Scripps Clinic, No. 10666 N Torrey Pines Road, La Jolla, CA 92037, United States. williamsonstrum@yahoo.com
Received: November 15, 2022 Peer-review started: November 15, 2022 First decision: January 2, 2023 Revised: January 18, 2023 Accepted: February 14, 2023 Article in press: February 14, 2023 Published online: February 21, 2023
Core Tip
Core Tip: Acute and chronic pancreatitis are leading causes for admissions to hospitals. This review identified four categories of crucial new findings including: (1) New genetic mutations (TRPV6); expected genetic outcomes; (2) new serum diagnostic markers-distinguishing pancreatitis associated with alcohol, and defining the impact of monocytes/macrophages on the inflammatory process; (3) critical innovations: In timing of PO low-fat, solid food intake immediately on admission; resolved concepts on fluid intake; non-operative treatment of infected necrosis; and (4) authoritarian recommendations for treatment of chronic pain. These advances offer opportunities to initiate newly-proven treatments to enhance outcomes and alter the natural history.
