Scientometrics
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2023; 29(40): 5593-5617
Published online Oct 28, 2023. doi: 10.3748/wjg.v29.i40.5593
Advances and key focus areas in gastric cancer immunotherapy: A comprehensive scientometric and clinical trial review (1999-2023)
Yao-Nan Li, Bin Xie, Ying Zhang, Ming-Hua He, Yang Xing, Dong-Mei Mu, Hong Wang, Rui Guo
Yao-Nan Li, Rui Guo, Clinical Laboratory, The First Hospital of Jilin University, Changchun 130012, Jilin Province, China
Bin Xie, Ying Zhang, Yang Xing, Hong Wang, Cancer Center, The First Hospital of Jilin University, Changchun 130012, Jilin Province, China
Ming-Hua He, College of Computer Science and Technology, Jilin University, Changchun 130012, Jilin Province, China
Dong-Mei Mu, Division of Clinical Research, The First Hospital of Jilin University, Changchun 130012, Jilin Province, China
Author contributions: Wang H and Guo R conceived the study and critically revised the manuscript; Li YN designed the study, performed statistical analyses, and drafted the manuscript; Xie B, Zhang Y, He MH, Mu DM, and Wang H designed the study and wrote the manuscript; Li YN, Guo R, and Wang H performed article retrieval and data interpretation; Mu DM conducted statistical assessment; and all the authors have read and agreed to the final version of the manuscript.
Supported by Natural Science Foundation of China, No. 81500116 and 81601449; and Jilin Science and Technique, No. 20200201472JC and YDZJ202301ZYTS092.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rui Guo, MD, Associate Professor, Clinical Laboratory, The First Hospital of Jilin University, No. 1 Xinmin Street, Chaoyang District, Changchun 130012, Jilin Province, China. guoruijdyy@jlu.edu.cn
Received: August 28, 2023
Peer-review started: August 28, 2023
First decision: September 11, 2023
Revised: September 25, 2023
Accepted: October 17, 2023
Article in press: October 17, 2023
Published online: October 28, 2023
Processing time: 60 Days and 0.5 Hours
Core Tip

Core Tip: In this study, we systematically analyzed studies related to immunotherapy for gastric cancer (GC). We used scientometrics to explore research hotspots in the field and summarize the current developmental status of GC immunotherapy, as well as the advantages and disadvantages of different immunotherapy modalities. We also compiled information on ongoing clinical trials and predicted future developmental trends in this field based on the direction and stage of these trials. This research can help advance our understanding of the latest progress and future development trends in the field, as well as provide scientific research recommendations.