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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2023; 29(32): 4851-4859
Published online Aug 28, 2023. doi: 10.3748/wjg.v29.i32.4851
Published online Aug 28, 2023. doi: 10.3748/wjg.v29.i32.4851
Role of non-Helicobacter pylori gastric Helicobacters in helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma
Fabian Fellipe Bueno Lemos, Marcel Silva Luz, Samuel Luca Rocha Pinheiro, Fabrício Freire de Melo, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista 45029094, Brazil
Kádima Nayara Teixeira, Campus Toledo, Universidade Federal do Paraná, Toledo 85919899, Brazil
Author contributions: Lemos FFB, and de Melo FF designed the manuscript; Lemos FFB, Luz MS, Pinheiro SLR, Teixeira KN, and de Melo FF contributed to the investigation; Lemos FFB, Silva Luz M, Pinheiro SLR, Teixeira KN, and de Melo FF contributed to the formal analysis; Lemos FFB, Luz MS, and Pinheiro SLR wrote the original draft; Lemos, FFB, and Luz MS were responsible for manuscript editing; Teixeira KN, and de Melo FF were responsible for manuscript review; and de Melo FF supervised the writing of the original draft.
Supported by Scientific Initiation Scholarship Programme of the Bahia State Research Support Foundation (FAPESB) , No. N°BOL1825/2022 ; Scientific Initiation Scholarship Programme of the National Council for Scientific and Technological Development (CNPq) , No. 129894/2022-2 ; CNPq Research Productivity Fellowship , No. 317005/2021-9 .
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fabrício Freire de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Estrada do Bem Querer, No. 3293-3391-Candeias, Vitória da Conquista 45029094, Brazil. freiremeloufba@gmail.com
Received: May 28, 2023
Peer-review started: May 28, 2023
First decision: July 8, 2023
Revised: July 18, 2023
Accepted: August 2, 2023
Article in press: August 2, 2023
Published online: August 28, 2023
Peer-review started: May 28, 2023
First decision: July 8, 2023
Revised: July 18, 2023
Accepted: August 2, 2023
Article in press: August 2, 2023
Published online: August 28, 2023
Core Tip
Core Tip: Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a type of non-hodgkin lymphoma that arises in the stomach. It has been well-established that Helicobacter pylori (H. pylori) infection plays a crucial role in the development of GML. However, a subset of patients diagnosed with GML are negative for H. pylori. In recent years, there has been growing interest in investigating the role of non-H. pylori gastric helicobacters (NHPHs) in the pathogenesis of H. pylori-negative GML. This minireview aims to explore the current understanding of the involvement of NHPHs in the development of GML and its potential responsiveness to bacterial eradication therapy.