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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 21, 2023; 29(3): 561-578
Published online Jan 21, 2023. doi: 10.3748/wjg.v29.i3.561
Published online Jan 21, 2023. doi: 10.3748/wjg.v29.i3.561
Small intestinal angiosarcoma on clinical presentation, diagnosis, management and prognosis: A case report and review of the literature
Xiao-Mei Ma, Yuan Yang, Guo-Zhi Wu, Ying-Wen Li, Xiao Yu, Xiao-Li Ma, Yu-Ping Wang, Qing-Hong Guo, Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
Xiao-Mei Ma, Yuan Yang, Guo-Zhi Wu, Ying-Wen Li, Xiao Yu, Xiao-Li Ma, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China
Bao-Shun Yang, Xu-Dong Hou, General Surgery Ward 5, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
Author contributions: Ma XM contributed to data analysis and manuscript writing; Yang BS contributed to conceptualization and methodology; Yang Y contributed to data curation and visualization; Wu GZ contributed to data curation, writing-original draft preparation; Li YW, Yu X, and Ma XL contributed to literature search and screening; Wang YP and Hou XD contributed to revised the manuscript and approved the final version; Guo QH contributed to supervision and final confirmation.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qing-Hong Guo, PhD, Chief Physician, Department of Gastro
Received: November 11, 2022
Peer-review started: November 11, 2022
First decision: November 24, 2022
Revised: December 3, 2022
Accepted: December 23, 2022
Article in press: December 23, 2022
Published online: January 21, 2023
Processing time: 61 Days and 20.5 Hours
Peer-review started: November 11, 2022
First decision: November 24, 2022
Revised: December 3, 2022
Accepted: December 23, 2022
Article in press: December 23, 2022
Published online: January 21, 2023
Processing time: 61 Days and 20.5 Hours
Core Tip
Core Tip: Small intestinal angiosarcoma is a rare malignant soft tissue tumor. We report a primary multifocal ileal angiosarcoma with metastases to the adrenal gland and lumbar spine. The patient died 4 mo after surgical resection. Further, we collected relevant case reports and analyzed statistically. We concluded that small intestinal angiosarcoma tend to occur in elderly men. Melena and anemia were the most common symptoms. The diagnosis depended on microscopic morphology and immunohistochemistry. CD31, CD34, factor VIII-related antigen, ETS-related gene, friend leukemia integration 1, and von Willebrand factor were valuable diagnostic markers. Surgery and chemotherapy could improve the prognosis of patients.