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World J Gastroenterol. Jan 21, 2023; 29(3): 503-507
Published online Jan 21, 2023. doi: 10.3748/wjg.v29.i3.503
Potential role of the microbiome in liver injury during COVID-19: Further research is needed
Marcos Roberto Tovani-Palone, Paolo Pedersini
Marcos Roberto Tovani-Palone, Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, India
Paolo Pedersini, IRCCS Fondazione Don Carlo Gnocchi, Milan 20148, Italy
Author contributions: Tovani-Palone MR contributed to study conception and design and writing of the manuscript; Pedersini P contributed to study design and critical review.
Conflict-of-interest statement: The authors declare no conflicts of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marcos Roberto Tovani-Palone, PhD, Academic Research, Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Poonamallee High Road, Velappanchavadi, Chennai 600077, India. marcos_palone@hotmail.com
Received: September 13, 2022
Peer-review started: September 13, 2022
First decision: October 19, 2022
Revised: November 30, 2022
Accepted: December 21, 2022
Article in press: December 21, 2022
Published online: January 21, 2023
Core Tip

Core Tip: Although different studies have associated coronavirus disease 2019 (COVID-19) with the occurrence of liver injury, the hepatic injury route during the COVID-19 course is not yet fully understood. Further research is needed to better understand the impacts of changes of the gut microbiota and immunology of COVID-19.