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World J Gastroenterol. Jul 28, 2023; 29(28): 4397-4404
Published online Jul 28, 2023. doi: 10.3748/wjg.v29.i28.4397
Application of single-cell omics in inflammatory bowel disease
Hengqi Betty Zheng
Hengqi Betty Zheng, Department of Pediatrics, Seattle Children’s Hospital, University of Washington, Seattle, WA 98105, United States
Author contributions: Zheng HB has written, revised, and approve the original and final versions of the manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hengqi Betty Zheng, MD, Assistant Professor, Department of Pediatrics, Seattle Children’s Hospital, University of Washington, 4800 Sandpoint Way NE, Seattle, WA 98105, United States. betty.zheng@gmail.com
Received: May 25, 2023
Peer-review started: May 25, 2023
First decision: June 14, 2023
Revised: June 27, 2023
Accepted: July 7, 2023
Article in press: July 7, 2023
Published online: July 28, 2023
Processing time: 61 Days and 16.4 Hours
Core Tip

Core Tip: Single-cell techniques and omics have taken off in the last few years and the ability to detect individual cellular transcript details has revolutionized the world of research. In the field of gastroenterology in just the last five years, several single-cell techniques have been applied to inflammatory bowel disease research with the identification of novel cellular immune players in the pathogenesis of both ulcerative colitis and Crohn’s disease.