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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2023; 29(25): 4072-4084
Published online Jul 7, 2023. doi: 10.3748/wjg.v29.i25.4072
Published online Jul 7, 2023. doi: 10.3748/wjg.v29.i25.4072
Non-invasive model for predicting high-risk esophageal varices based on liver and spleen stiffness
Long-Bao Yang, Xin Gao, Hong Li, Xin-Xing Tantai, Fen-Rong Chen, Lei Dong, Zhong-Cao Wei, Chen-Yu Liu, Yan Wang, Department of Gastroenterology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China
Xu-Sheng Dang, Department of Emergency, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China
Author contributions: Yang LB and Gao X contributed equally to this work; Li H, Dong L, and Dang XS designed the research study; Liu CY and Gao X performed the research; Tantai XX and Wei ZC contributed new reagents and analytic tools; Yang LB, Wang Y, and Chen FR analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Supported by the Shaanxi Provincial Key Research and Development Plan , No. 2020SF-159 .
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the Second Affiliated Hospital of Xi’an Jiaotong University (approval No. 2017-445).
Informed consent statement: This study is a retrospective study; thus, the ethics committee has exempted the informed consent of the patients.
Conflict-of-interest statement: There was no any interests conflicts.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Wang, MD, Assistant Professor, Department of Gastroenterology, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 of Xiwu Road, Xi’an 710004, Shaanxi Province, China. sarrye@163.com
Received: April 23, 2023
Peer-review started: April 23, 2023
First decision: May 15, 2023
Revised: May 20, 2023
Accepted: June 2, 2023
Article in press: June 2, 2023
Published online: July 7, 2023
Processing time: 65 Days and 17.3 Hours
Peer-review started: April 23, 2023
First decision: May 15, 2023
Revised: May 20, 2023
Accepted: June 2, 2023
Article in press: June 2, 2023
Published online: July 7, 2023
Processing time: 65 Days and 17.3 Hours
Core Tip
Core Tip: The non-invasive prediction model for predicting high risk esophageal varices (HEVs) in patients with viral cirrhosis was successfully established based on the spleen stiffness measurement and liver stiffness measurement. It is a novel model that has not been reported. The model was shown to be better than previous prediction models. The new model is reliable in predicting HEVs and can be used as an alternative to routine upper gastrointestinal endoscopy screening, which is helpful for clinical decision making.