Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2023; 29(18): 2836-2849
Published online May 14, 2023. doi: 10.3748/wjg.v29.i18.2836
Endoscopic and pathological characteristics of de novo colorectal cancer: Retrospective cohort study
Shi-Yang Li, Mei-Qi Yang, Yi-Ming Liu, Ming-Jun Sun, Hui-Jing Zhang
Shi-Yang Li, Mei-Qi Yang, Yi-Ming Liu, Ming-Jun Sun, Hui-Jing Zhang, Department of Endoscopy, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Zhang HJ had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis; Zhang HJ, Li SY, and Yang MQ were responsible for protocol/project development; Li SY, Yang MQ, and Zhang HJ performed data analysis; Li SY, Yang MQ, Liu YM, and Sun MJ performed data collection or management; Yang MQ and Zhang HJ were responsible for manuscript writing/editing; Li SY and Yang MQ, these two authors, contributed equally to this work.
Supported by Natural Science Foundation of Liaoning Province, China, No. 2022-YGJC-71.
Institutional review board statement: The study was reviewed and approved by the Research Ethics Committee of the First Affiliated Hospital of China Medical University Institutional Review Board, No. [2021]2021-68-2.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Participants gave informed consent for data sharing.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Jing Zhang, MD, Professor, Department of Endoscopy, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110001, Liaoning Province, China. hjzhang@cmu.edu.cn
Received: March 28, 2023
Peer-review started: March 28, 2023
First decision: April 10, 2023
Revised: April 14, 2023
Accepted: April 19, 2023
Article in press: April 19, 2023
Published online: May 14, 2023
Core Tip

Core Tip:De novo colorectal cancer (CRC) is a specific tumor with a small lesion. Many different features of de novo CRCs exist to distinguish them from non-neoplastic polyps. Moreover, the study highlights that de novo CRCs have special endoscopic and pathological features that distinguish them from traditional adenocarcinomas. Different pit pattern types indicate various tumor types; for example, the III-type pit pattern often occurs in tubular adenomas. For CRCs, invasion depth evaluation is a vital issue. Computed tomography imaging and endoscopic ultrasound are used for judging invasive depth. Besides, chicken skin mucosa may also be a risk factor.