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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2023; 29(15): 2349-2358
Published online Apr 21, 2023. doi: 10.3748/wjg.v29.i15.2349
Published online Apr 21, 2023. doi: 10.3748/wjg.v29.i15.2349
Repeat peroral endoscopic myotomy with simultaneous submucosal and muscle dissection as a salvage option for recurrent achalasia
Yun-Juan Lin, Department of Gastroenterology and Hepatology, Chinese PLA General Hospital and Chinese PLA Medical School, Beijing 100853, China
Sheng-Zhen Liu, Long-Song Li, Ke Han, Bo-Zong Shao, En-Qiang Linghu, Ning-Li Chai, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Chai NL was the guarantor and designed the study; Lin YJ and Liu SZ participated in the acquisition, analysis, and interpretation of the data, and drafted the initial manuscript; Li LS, Han K, and Shao BZ revised the article critically for important intellectual content; Linghu EQ and Chai NL were the patient’s endoscopists; and all authors read and approved the final version.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Chinese PLA General Hospital (Approval No. S2021-207-01).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning-Li Chai, MD, Chief Physician, Professor, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. chainingli@vip.163.com
Received: January 15, 2023
Peer-review started: January 15, 2023
First decision: February 7, 2023
Revised: February 20, 2023
Accepted: March 29, 2023
Article in press: March 29, 2023
Published online: April 21, 2023
Processing time: 88 Days and 21.5 Hours
Peer-review started: January 15, 2023
First decision: February 7, 2023
Revised: February 20, 2023
Accepted: March 29, 2023
Article in press: March 29, 2023
Published online: April 21, 2023
Processing time: 88 Days and 21.5 Hours
Core Tip
Core Tip: For recurrent achalasia after initial peroral endoscopic myotomy (POEM) failure, repeat POEM (Re-POEM) has been reported as a potential treatment option. However, severe interlayer adhesions caused by previous procedures impede the successful establishment of a submucosal tunnel. In this study, we retrospectively analyzed the data of patients who had persistent or recurrent symptoms after initial POEM and underwent Re-POEM or Re-POEM with simultaneous submucosal and muscle dissection (Re-POEM-SSMD). The results show that Re-POEM-SSMD could serve as an effective and safe salvage option for patients with recurrent achalasia when conventional POEM procedures are impeded by severe interlayer adhesions.