Letter to the Editor
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2022; 28(9): 973-975
Published online Mar 7, 2022. doi: 10.3748/wjg.v28.i9.973
Radiomics-clinical nomogram for response to chemotherapy in synchronous liver metastasis of colorectal cancer: Good, but not good enough
Han Yan, Tu-Nan Yu
Han Yan, Department of Colorectal Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Tu-Nan Yu, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: All authors helped to prepare this manuscript; Yan H and Yu TN contributed to manuscript writing, drafting conception and design.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest, and there was no fund supporting this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tu-Nan Yu, MD, PhD, Doctor, Statistician, Surgeon, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang Province, China. 3314006@zju.edu.cn
Received: October 31, 2021
Peer-review started: October 31, 2021
First decision: December 12, 2021
Revised: January 3, 2022
Accepted: January 29, 2022
Article in press: January 29, 2022
Published online: March 7, 2022
Core Tip

Core Tip: There remains a persistent unmet need to detect the disease nonresponse subgroup before adjuvant therapy in synchronous liver metastasis patients with colorectal cancer. Ma’s radiomics-clinical nomogram is currently not good enough, as the study did not explore the statuses of certain tumor genes, did not validate the nomogram in left- and right-sided tumors separately, and used tumor size shrinkage rather than resectability to judge the success of adjuvant therapy.