Systematic Reviews
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2022; 28(46): 6599-6618
Published online Dec 14, 2022. doi: 10.3748/wjg.v28.i46.6599
Correlation between COVID-19 and hepatitis B: A systematic review
Yan-Fei He, Zhi-Gang Jiang, Ni Wu, Ning Bian, Jun-Lin Ren
Yan-Fei He, Ni Wu, Ning Bian, Health Management Center, The Sixth Medical Center, Chinese PLA General Hospital, Beijing 100048, China
Zhi-Gang Jiang, Department of Statistics, Zunyi Medical University, Guizhou 563006, Guizhou Province, China
Jun-Lin Ren, Department of Infection Control, The Sixth Medical Center, Chinese PLA General Hospital, Beijing 100048, China
Author contributions: He YF designed the study, reviewed the literature, and drafted the manuscript; Jiang ZG and Wu N retrieved and summarized the literature; Ren JL and Bian N advised on the review and reviewed the final manuscript; and all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Fei He, MD, Associate Chief Physician, Doctor, Health Management Center, The Sixth Medical Center, Chinese PLA General Hospital, No. 6 Fucheng Road, Haidian District, Beijing 100048, China. heyanfeilc@163.com
Received: September 11, 2022
Peer-review started: September 11, 2022
First decision: October 19, 2022
Revised: October 29, 2022
Accepted: November 19, 2022
Article in press: November 19, 2022
Published online: December 14, 2022
Processing time: 88 Days and 3.8 Hours
Core Tip

Core Tip: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and hepatitis B virus (HBV) infections are two major current global public health crises. Both infection with SARS-CoV-2 and infection with HBV can cause liver damage. There are conflicting views on whether HBV infection aggravates the prognosis of patients with coronavirus disease 2019 (COVID-19). There is a potential association between COVID-19 and hepatitis B. Clarification of this association could benefit these special patients with SARS-CoV-2 and HBV co-infection.