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World J Gastroenterol. Dec 14, 2022; 28(46): 6497-6511
Published online Dec 14, 2022. doi: 10.3748/wjg.v28.i46.6497
Nanotechnology for colorectal cancer detection and treatment
Purnima Gogoi, Geetika Kaur, Nikhlesh K Singh
Purnima Gogoi, Geetika Kaur, Nikhlesh K Singh, Integrative Biosciences Center, OVAS, Wayne State University School of Medicine, Detroit, MI 48202, United States
Author contributions: Gogoi P, Kaur G and Singh NK contributed to writing the original draft, review and editing of the manuscript and visual representation of the data; Singh NK contributed to conceptualization, supervision and funding acquisition; and all authors have read and approved the final version of the manuscript.
Supported by the National Institutes of Health grant, R01EY029709.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nikhlesh K Singh, DVM, PhD, Associate Professor, Integrative Biosciences Center, OVAS, Wayne State University School of Medicine, 6135 Woodward Avenue, Detroit, MI 48202, United States. nsingh2@wayne.edu
Received: September 13, 2022
Peer-review started: September 13, 2022
First decision: October 19, 2022
Revised: October 28, 2022
Accepted: November 18, 2022
Article in press: November 18, 2022
Published online: December 14, 2022
Core Tip

Core Tip: Colorectal cancer (CRC) is the third most diagnosed cancer and the second leading cause of cancer-related mortality in the United States. Genetic and environmental risk factors play a significant role in the development of CRC. This review discusses the recent insights into nanotechnology-based methods for screening, detection and treatment of CRC. This review aims to provide knowledge on the advancement of nanotechnology in CRC and as a starting point for researchers to think about new therapeutic approaches using nanotechnology.