Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 7, 2022; 28(45): 6410-6420
Published online Dec 7, 2022. doi: 10.3748/wjg.v28.i45.6410
Meta-analysis on the epidemiology of gastroesophageal reflux disease in China
Tai-Liang Lu, Shao-Rong Li, Jia-Min Zhang, Chao-Wu Chen
Tai-Liang Lu, Chao-Wu Chen, Department of Gastrointestinal Surgery, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410005, Hunan Province, China
Shao-Rong Li, Jia-Min Zhang, Operating Room, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong Province, China
Author contributions: Lu TL and Chen CW contributed to the study design and drafting of the manuscript; Lu TL, Zhang JM, Li SR and Chen CW contributed to the data collection; Lu TL and Li SR contributed to the analysis and interpretation of data; Zhang JM and Li SR contributed to the critical revision of the manuscript; All the authors did approval of the final version for publication.
Conflict-of-interest statement: The authors declare no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chao-Wu Chen, MD, Chief Physician, Department of Gastrointestinal Surgery, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, No. 139 Renmin Road, Changsha 410005, Hunan Province, China. dr.chencw@hunnu.edu.cn
Received: September 7, 2022
Peer-review started: September 7, 2022
First decision: October 19, 2022
Revised: October 27, 2022
Accepted: November 16, 2022
Article in press: November 16, 2022
Published online: December 7, 2022
Core Tip

Core Tip: The overall pooled prevalence of gastroesophageal reflux disease (GERD) was 8.7% in China. The prevalence was higher in the west and east than in the centre, and there may be a local spatial autocorrelation between the Qinghai-Tibet Plateau and the southeast. GERD was correlated with gastric and oesophageal tumours in spatial distribution.