Copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2022; 28(29): 3960-3970
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3960
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3960
Radiomics for differentiating tumor deposits from lymph node metastasis in rectal cancer
Yong-Chang Zhang, Department of Radiology, Chengdu Seventh People’s Hospital, Chengdu 610213, Sichuan Province, China
Yong-Chang Zhang, Mou Li, Yu-Mei Jin, Bin Song, Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Jing-Xu Xu, Chen-Cui Huang, Department of Research Collaboration, R&D center, Beijing Deepwise & League of PHD Technology Co., Ltd, Beijing 100080, China
Author contributions: Song B designed the research; Zhang YC and Jin YM collected the data; Li M, Xu JX, and Huang CC analyzed the data; Zhang YC and Li M wrote the paper; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of West China Hospital of Sichuan University, No. 1159.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: Authors Jing-Xu Xu and Chen-Cui Huang are employed by the company Beijing Deepwise & League of PHD Technology Co., Ltd; the remaining authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bin Song, MD, PhD, Chief Doctor, Professor, Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. songlab_radiology@163.com
Received: December 29, 2021
Peer-review started: December 29, 2021
First decision: March 10, 2022
Revised: March 28, 2022
Accepted: July 6, 2022
Article in press: July 6, 2022
Published online: August 7, 2022
Processing time: 217 Days and 1.6 Hours
Peer-review started: December 29, 2021
First decision: March 10, 2022
Revised: March 28, 2022
Accepted: July 6, 2022
Article in press: July 6, 2022
Published online: August 7, 2022
Processing time: 217 Days and 1.6 Hours
Core Tip
Core Tip: In this study, a radiomics model based on the largest peritumoral nodule was developed to preoperatively differentiate tumor deposits (TDs) from lymph node (LN) metastasis in patients with rectal cancer. This model demonstrated good performance in both the training and validation cohorts. However, its performance decreased with the diagnosis of the double-positive patients. In summary, this model can be helpful for differentiating TDs from LN metastasis.