Minireviews
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World J Gastroenterol. Aug 7, 2022; 28(29): 3793-3802
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3793
Epidemiologic and socioeconomic factors impacting hepatitis B virus and related hepatocellular carcinoma
Bipul Gnyawali, Antoinette Pusateri, Ashley Nickerson, Sajid Jalil, Khalid Mumtaz
Bipul Gnyawali, Department of Medicine, Kettering Medical Center, Dayton, OH 45342, United States
Antoinette Pusateri, Ashley Nickerson, Sajid Jalil, Khalid Mumtaz, Department of Medicine, The Ohio State University, Columbus, OH 43210, United States
Author contributions: Gnyawali B and Mumtaz K contributed to the conception of the review; Gnyawali B and Pusateri A performed a review of the current literature; Gnyawali B drafted the manuscript; Pusateri A, Nickerson A, Mumtaz K, and Jalil S added key information and revised the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: There are no conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Khalid Mumtaz, MBBS, MSc, Associate Professor, Department of Medicine, The Ohio State University, 395 W. 12th Avenue, 262 Suite, Columbus, OH 43210, United States. khalid.mumtaz@osumc.edu
Received: January 18, 2022
Peer-review started: January 18, 2022
First decision: March 8, 2022
Revised: April 10, 2022
Accepted: July 11, 2022
Article in press: July 11, 2022
Published online: August 7, 2022
Processing time: 197 Days and 3.8 Hours
Core Tip

Core Tip: While many studies in the past have analyzed the impact of various epidemiological and socioeconomic factors on viral hepatitis and hepatocellular carcinoma (HCC), this minireview is the first to adopt a global perspective in highlighting the impact of both epidemiologic and socioeconomic factors on current trends in chronic hepatitis B and related HCC. We highlight trends in incidence, prevalence and mortality of chronic hepatitis B seen throughout the world in the past few decades and the disparity in healthcare distribution and outcomes between different populations.