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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2022; 28(24): 2654-2666
Published online Jun 28, 2022. doi: 10.3748/wjg.v28.i24.2654
Published online Jun 28, 2022. doi: 10.3748/wjg.v28.i24.2654
Drug-induced autoimmune hepatitis: A minireview
Chin Kimg Tan, Danielle Ho, Rahul Kumar, Gastroenterology and Hepatology, Changi General Hospital, Singapore 529889, Singapore
Chin Kimg Tan, Rahul Kumar, Medicine Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Singapore 529889, Singapore
Lai Mun Wang, Section of Pathology, Department of Laboratory Medicine, Changi General Hospital, Singapore 529889, Singapore
Lai Mun Wang, Pathology Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Singapore 529889, Singapore
Author contributions: Kumar R and Tan CK conceptualized the study; Tan CK, Ho D, and Kumar R wrote the initial manuscript; Wand LM provided critical input and histo-pathological slides for the manuscript; all authors were involved in the critical revision.
Conflict-of-interest statement: All authors have no relevant conflict of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rahul Kumar, FRCP, Assistant Professor, Gastroenterology and Hepatology, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore.
Received: August 5, 2021
Peer-review started: August 5, 2021
First decision: September 4, 2021
Revised: September 15, 2021
Accepted: May 14, 2022
Article in press: May 14, 2022
Published online: June 28, 2022
Processing time: 322 Days and 22.3 Hours
Peer-review started: August 5, 2021
First decision: September 4, 2021
Revised: September 15, 2021
Accepted: May 14, 2022
Article in press: May 14, 2022
Published online: June 28, 2022
Processing time: 322 Days and 22.3 Hours
Core Tip
Core Tip: Drug-induced autoimmune hepatitis is uncommon in clinical practice but may have devastating consequences. It is important to distinguish drug-induced autoimmune hepatitis from idiopathic autoimmune hepatitis as the former may not require prolong course of immunosuppressant. This minireview highlights the key differences between these two closely-linked entities.