Basic Study
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World J Gastroenterol. May 21, 2022; 28(19): 2112-2122
Published online May 21, 2022. doi: 10.3748/wjg.v28.i19.2112
Snare-assisted flexible endoscope in trans-gastric endoscopic gallbladder-preserving surgery: A pilot animal study
Xian-Wen Guo, Yun-Xiao Liang, Peng-Yu Huang, Lie-Xin Liang, Yi-Qing Zeng, Zhen Ding
Xian-Wen Guo, Zhen Ding, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Xian-Wen Guo, Yun-Xiao Liang, Peng-Yu Huang, Lie-Xin Liang, Yi-Qing Zeng, Department of Gastroenterology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Guo XW and Ding Z contributed equally to this work; Guo XW and Ding Z were responsible for the study concept and design, including endoscopic procedures; all authors conducted the endoscopic operations together; Guo XW drafted the manuscript; Ding Z revised and finalized the manuscript.
Supported by National Natural Science Foundation of China, No. 82060104; and Construction of Guangxi Clinical Medical Research Center for Digestive Diseases, No. AD17129027.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the People's Hospital of Guangxi Zhuang Autonomous Region and the Ethics Committee of the Tongji Medical College, No. KY-LW-2019-4, [2020]-S322.
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of People's Hospital of Guangxi Zhuang Autonomous Region (No. KY-LW-2019-4) and the Institutional Animal Care and Committee at Huazhong University of Science and Technology Tongji Medical College (No. 2625).
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen Ding, PhD, Chief Doctor, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. docd720@126.com
Received: December 19, 2021
Peer-review started: December 19, 2021
First decision: March 10, 2022
Revised: March 23, 2022
Accepted: April 15, 2022
Article in press: April 15, 2022
Published online: May 21, 2022
Core Tip

Core Tip: This study aimed to evaluate the feasibility and safety of a new surgical method, “snare-assisted pure natural orifice transluminal endoscopic surgery (NOTES) gallbladder-preserving surgery”. Eight miniature pigs were randomly divided into an experimental group [snare assisted (SA)] and a control group. The total operating time, gallbladder incision blood loss, gallbladder disorientation time, gallbladder incision closure time, and workload scores on the National Aeronautics and Space Administration-Task Load Index were significantly reduced in the SA group. These results indicated that snare-assisted pure NOTES gallbladder-preservation surgery reduced the difficulty of the operation, shortened the operation time, and did not increase complications.