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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2022; 28(11): 1102-1112
Published online Mar 21, 2022. doi: 10.3748/wjg.v28.i11.1102
Published online Mar 21, 2022. doi: 10.3748/wjg.v28.i11.1102
Impaired coagulation, liver dysfunction and COVID-19: Discovering an intriguing relationship
Damiano D’Ardes, Ilaria Rossi, Marco Bucci, Maria Teresa Guagnano, Francesco Cipollone, “Clinica Medica” Institute, Department of Medicine and Aging Sciences, “G. D’Annunzio” University of Chieti-Pescara, Chieti 66100, Italy
Andrea Boccatonda, Giulio Cocco, Stefano Fabiani, Cosima Schiavone, Unit of Ultrasound, “G. D’Annunzio” University of Chieti-Pescara, Chieti 66100, Italy
Author contributions: All authors have designed, written and revised the manuscript.
Conflict-of-interest statement: There is no conflict of interest associated with the authors of this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Damiano D’Ardes, MD, Doctor, Research Fellow, “Clinica Medica” Institute, Department of Medicine and Aging Sciences, “G. D’Annunzio” University of Chieti-Pescara, Chieti 66100, Italy. 89damiano@gmail.com
Received: April 18, 2021
Peer-review started: April 18, 2021
First decision: July 27, 2021
Revised: August 9, 2021
Accepted: February 15, 2022
Article in press: February 15, 2022
Published online: March 21, 2022
Processing time: 332 Days and 6.5 Hours
Peer-review started: April 18, 2021
First decision: July 27, 2021
Revised: August 9, 2021
Accepted: February 15, 2022
Article in press: February 15, 2022
Published online: March 21, 2022
Processing time: 332 Days and 6.5 Hours
Core Tip
Core Tip: Evidence in the literature suggests a contribution of the severe acute respiratory syndrome coronavirus 2 to the pathophysiology of liver injury, atherothrombosis and coagulation disorders. This minireview explores the possible mechanisms by which these alterations are generated during coronavirus disease 2019 according to current knowledge.