Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2021; 27(31): 5126-5151
Published online Aug 21, 2021. doi: 10.3748/wjg.v27.i31.5126
Endoscopic diagnosis and treatment of gastric dysplasia and early cancer: Current evidence and what the future may hold
Edward Young, Hamish Philpott, Rajvinder Singh
Edward Young, Hamish Philpott, Rajvinder Singh, Department of Gastroenterology, Lyell McEwin Hospital, Elizabeth Vale 5112, SA, Australia
Edward Young, Rajvinder Singh, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, SA, Australia
Author contributions: Young E collected the data and wrote the manuscript; Philpott H assisted with writing of the manuscript and reviewing for submission; Singh R developed the construct of the review, assisted with writing of the manuscript and reviewing for submission
Conflict-of-interest statement: No authors have any conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Edward Young, MBBS, Doctor, Department of Gastroenterology, Lyell McEwin Hospital, Haydown Road, Elizabeth Vale 5112, SA, Australia. edward.young@sa.gov.au
Received: March 31, 2021
Peer-review started: March 31, 2021
First decision: June 23, 2021
Revised: July 7, 2021
Accepted: August 5, 2021
Article in press: August 5, 2021
Published online: August 21, 2021
Processing time: 139 Days and 16.5 Hours
Core Tip

Core Tip: There have been numerous recent advances in the endoscopic detection, characterization and treatment of precancerous gastric lesions and early gastric cancers. Accumulating evidence suggests that endoscopic submucosal dissection results in at least equivalent disease-related outcomes with a marked reduction in morbidity compared to gastrectomy. Supportive data are robust in regions with high gastric cancer prevalence, however a paucity of western data results in inconsistencies in clinical practice in these regions. This article serves to review existing evidence regarding endoscopic imaging and therapeutics in gastric cancer, as well as identify future areas for research and development.