Meta-Analysis
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2021; 27(25): 3925-3939
Published online Jul 7, 2021. doi: 10.3748/wjg.v27.i25.3925
Endoscopic submucosal dissection vs endoscopic mucosal resection for colorectal polyps: A meta-analysis and meta-regression with single arm analysis
Xiong Chang Lim, Kameswara Rishi Yeshayahu Nistala, Cheng Han Ng, Snow Yunni Lin, Darren Jun Hao Tan, Khek-Yu Ho, Choon-Seng Chong, Mark Muthiah
Xiong Chang Lim, Kameswara Rishi Yeshayahu Nistala, Cheng Han Ng, Snow Yunni Lin, Darren Jun Hao Tan, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
Khek-Yu Ho, Mark Muthiah, Department of Medicine, National University Hospital, Singapore 119074, Singapore
Choon-Seng Chong, Department of Surgery, National University Hospital, Singapore 119074, Singapore
Author contributions: Lim XC, Nistala KRY, Ng CH, Ho KY, Muthiah M and Chong CS were involved in the conceptualization of the paper; Lim XC and Nistala KRY were involved in the acquisition of data; Lim XC, Nistala KRY, Ng CH, Lin SY, Tan DJH, Ho KY, Muthiah M and Chong CS were involved in the data analysis and interpretation; Lim XC, Nistala KRY and Ng CH were involved in writing of first draft; Ho KY, Muthiah M, Chong CS were involved in the reviewing of the drafts; all eight authors approved the final manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mark Muthiah, MBBS, MRCP, MMed, Assistant Professor, Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. mdcmdm@nus.edu.sg
Received: February 24, 2021
Peer-review started: February 24, 2021
First decision: April 18, 2021
Revised: April 21, 2021
Accepted: June 1, 2021
Article in press: June 1, 2021
Published online: July 7, 2021
Processing time: 131 Days and 19.3 Hours
Core Tip

Core Tip: The present study is the most extensive meta-analysis evaluating the surgical, histological, and oncological outcomes of endoscopic submucosal dissection (ESD) in comparison to endoscopic mucosal resection (EMR) in the treatment of colorectal polyps. Our analysis also showed the increased proficiency in performing ESD and EMR in Japan as compared to the rest of the world.