Burden of venous thromboembolism in patients with pancreatic cancer

doi:10.3748/wjg.v27.i19.2325

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2021; 27(19): 2325-2340
Published online May 21, 2021. doi: 10.3748/wjg.v27.i19.2325

Burden of venous thromboembolism in patients with pancreatic cancer

Corinne Frere

Corinne Frere, Department of Haematology, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris F-75013, France

Corinne Frere, INSERM UMRS_1166, Institute of Cardiometabolism And Nutrition, GRC 27 GRECO, Sorbonne Université, Paris F-75013, France

Corinne Frere, Groupe Francophone Thrombose et Cancer, Saint-Louis Hospital, Paris F-75010, France

Author contributions: Frere C performed the literature review and drafted the manuscript.

Conflict-of-interest statement: The author declare she has no conflict of interest relevant to the content of this paper to disclose.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Corinne Frere, MD, PhD, Assistant Professor, Department of Haematology, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, Paris F-75013, France. corinne.frere@aphp.fr

Received: January 24, 2021
Peer-review started: January 24, 2021
First decision: February 22, 2021
Revised: February 28, 2021
Accepted: April 22, 2021
Article in press: April 22, 2021
Published online: May 21, 2021
Processing time: 108 Days and 18.7 Hours

Core Tip

Core Tip: Venous thromboembolism (VTE) is a common but potentially life-threatening complication in patients with Pancreatic cancer (PC). There is an urgent need to raise awareness on this underrecognized issue. This review discusses the incidence and risk factors of VTE in PC patients, and the results from recent clinical trials for the primary prophylaxis and treatment of VTE in cancer patients supporting the most recent clinical practice guidelines.