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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2020; 26(9): 960-972
Published online Mar 7, 2020. doi: 10.3748/wjg.v26.i9.960
Published online Mar 7, 2020. doi: 10.3748/wjg.v26.i9.960
Differentiation of atypical hepatic hemangioma from liver metastases: Diagnostic performance of a novel type of color contrast enhanced ultrasound
Xiao-Feng Wu, Xiu-Mei Bai, Wei Yang, Hong Wang, Wei Wu, Min-Hua Chen, Kun Yan, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing 100142, China
Yu Sun, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing 100142, China
Author contributions: All authors performed the research; Wu XF, Bai XM and Yang W wrote the manuscript; Wu XF, Bai XM and Wang H performed the color contrast ultrasound and data analysis; Yang W, Wu W, Chen MH, and Yan K conceived and designed the study, performed the examinations, and the data analysis; Sun Y performed the pathologic analysis. Wu XF and Bai XM contributed equally to this work.
Supported by Capital Medical Development Program , No. 2018-2-2154 ; and National Natural Science Foundation of China , No. 81773286 .
Institutional review board statement: This study was reviewed and approved by the Peking University School of Oncology
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei Yang, MD, Professor, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Ultrasound, Peking University Cancer Hospital & Institute, Number 52 Fucheng Road, District of Haidian, Beijing 100142, China. 13681408183@163.com
Received: November 28, 2019
Peer-review started: November 28, 2019
First decision: December 23, 2019
Revised: January 12, 2020
Accepted: January 19, 2020
Article in press: January 19, 2020
Published online: March 7, 2020
Processing time: 99 Days and 0.3 Hours
Peer-review started: November 28, 2019
First decision: December 23, 2019
Revised: January 12, 2020
Accepted: January 19, 2020
Article in press: January 19, 2020
Published online: March 7, 2020
Processing time: 99 Days and 0.3 Hours
Core Tip
Core tip: Features of atypical hemangioma and liver metastases on routine contrast-enhanced ultrasound are complicated. Color parametric imaging is a new approach that provides specific information on hemodynamic features. The following color parametric imaging features were significantly different between atypical liver hemangioma and liver metastases analyzed by staff and resident radiologists: Peripheral nodular enhancement, mosaic/chaotic enhancement and feeding artery. These findings could help radiologists and even senior radiologists with better identification of the diseases.