Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2020; 26(5): 466-477
Published online Feb 7, 2020. doi: 10.3748/wjg.v26.i5.466
Endoscopic Kyoto classification of Helicobacter pylori infection and gastric cancer risk diagnosis
Osamu Toyoshima, Toshihiro Nishizawa, Kazuhiko Koike
Osamu Toyoshima, Toshihiro Nishizawa, Department of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan
Osamu Toyoshima, Kazuhiko Koike, Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Toshihiro Nishizawa, Department of Gastroenterology and Hepatology, International University of Health and Welfare, Mita Hospital, Tokyo 108-8329, Japan
Author contributions: Toyoshima O reviewed the literature and wrote the article; Nishizawa T revised and edited the article; Koike K revised and approved the final article.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Osamu Toyoshima, MD, Director, Doctor, Department of Gastroenterology, Toyoshima Endoscopy Clinic, 6-17-5 Seijo, Setagaya-ku, Tokyo 157-0066, Japan.
Received: December 30, 2019
Peer-review started: December 30, 2019
First decision: January 11, 2020
Revised: January 15, 2020
Accepted: January 19, 2020
Article in press: January 19, 2020
Published online: February 7, 2020
Core Tip

Core tip: The Kyoto classification organizes endoscopic findings based on Helicobacter pylori (H. pylori) infection. The score of the Kyoto classification is the sum of scores of five endoscopic findings (atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness with or without regular arrangement of collecting venules) and ranges from 0 to 8. A high score is believed to reflect a higher risk of current H. pylori infection and gastric cancer. A Kyoto classification score of 0 indicates no H. pylori infection. A Kyoto classification score of ≥ 2 indicates current H. pylori infection. A Kyoto classification score of ≥ 4 might indicate gastric cancer risk.