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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 21, 2020; 26(35): 5375-5386
Published online Sep 21, 2020. doi: 10.3748/wjg.v26.i35.5375
Published online Sep 21, 2020. doi: 10.3748/wjg.v26.i35.5375
Gastrointestinal tract injuries after thermal ablative therapies for hepatocellular carcinoma: A case report and review of the literature
Teresa Marzia Rogger, Andrea Michielan, Sandro Sferrazza, Cecilia Pravadelli, Luisa Moser, Flora Agugiaro, Giovanni Vettori, Sonia Seligmann, Elettra Merola, Giovanni de Pretis, Department of Surgery, Gastroenterology and Digestive Endoscopy Unit, Santa Chiara Hospital, Trento 38122, Italy
Marcello Maida, Gastroenterology and Endoscopy Unit, S.Elia-Raimondi Hospital, Caltanissetta, Caltanissetta 93100, Italy
Francesco Antonio Ciarleglio, Alberto Brolese, Department of Surgery, Hepato-biliary Surgery Unit, Santa Chiara Hospital, Trento 38122, Italy
Author contributions: Pravadelli C, Michielan A and Sferrazza S contributed to study concept and design; Rogger TM, Michielan A, Sferrazza S, Pravadelli C, Maida M and Ciarleglio FA contributed to drafting of the manuscript; Moser L, Seligmann S, Vettori G, Agugiaro F and Merola E contributed to critical revision of the manuscript for important intellectual content; Brolese A and de Pretis G contributed to study supervision and final approval.
Informed consent statement: Informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare no conflict of interest related to this publication.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Andrea Michielan, MD, Doctor, Department of Surgery, Gastroenterology and Digestive Endoscopy Unit, Santa Chiara Hospital, Largo Medaglie D’Oro 9, Trento 38122, Italy. andrea.michielan@apss.tn.it
Received: June 28, 2020
Peer-review started: June 28, 2020
First decision: July 28, 2020
Revised: August 11, 2020
Accepted: September 1, 2020
Article in press: September 1, 2020
Published online: September 21, 2020
Peer-review started: June 28, 2020
First decision: July 28, 2020
Revised: August 11, 2020
Accepted: September 1, 2020
Article in press: September 1, 2020
Published online: September 21, 2020
Core Tip
Core Tip: Thermal ablative therapies have a key role in the treatment algorithm for hepatocellular carcinoma, and besides their efficacy and tolerability, several studies have proven their overall safety. Nevertheless, albeit rarely, a number of complications have been reported and awareness is crucial to proposing the best treatment for each patient. We report the unusual case of a gastric perforation that was treated in our division and how it was managed with an endoscopic over-the-scope clip for the first time. The literature review aims to discuss the most relevant published data on gastrointestinal tract injuries after thermal ablation therapies.