Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2020; 26(30): 4489-4500
Published online Aug 14, 2020. doi: 10.3748/wjg.v26.i30.4489
Simultaneous transcatheter arterial chemoembolization and portal vein embolization for patients with large hepatocellular carcinoma before major hepatectomy
Cheng-Wu Zhang, Chang-Wei Dou, Xin-Long Zhang, Xi-Qiang Liu, Dong-Shen Huang, Zhi-Ming Hu, Jie Liu
Cheng-Wu Zhang, Chang-Wei Dou, Xi-Qiang Liu, Dong-Shen Huang, Zhi-Ming Hu, Jie Liu, Department of Hepatopancreatobiliary Surgery and Minimally Invasive Surgery, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Xin-Long Zhang, Department of General Surgery, Aksu Area First Hospital, Aksu 843000, Xinjiang Uygur Autonomous Region, China
Author contributions: Zhang CW, Dou CW and Zhang XL contributed equally to this work; Zhang CW, Huang DS and Liu J designed this study; Dou CW and Liu J wrote the manuscript; Zhang XL, Hu ZM and Liu XQ prepared the tables and figures.
Supported by the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission, No. 2016KYA009 and No. 2020KY044.
Institutional review board statement: The study was approved by the ethics committee of Zhejiang Provincial People’s Hospital (No.2019KY181) and followed the declaration of Helsinki.
Informed consent statement: Written informed consent was obtained from all enrolled patients.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jie Liu, MD, Associate Professor, Surgeon, Department of Hepatopancreatobiliary Surgery and Minimally Invasive Surgery, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, No. 481 Binwen Road, Binjiang District, Hangzhou 310014, Zhejiang Province, China. atianlx1226@163.com
Received: March 30, 2020
Peer-review started: March 30, 2020
First decision: May 29, 2020
Revised: June 10, 2020
Accepted: July 14, 2020
Article in press: July 14, 2020
Published online: August 14, 2020
Processing time: 137 Days and 5.2 Hours
Core Tip

Core tip: Simultaneous transarterial chemoembolization (TACE) and portal vein embolization (PVE) is a safe and effective approach to increase the future liver remnant volume quickly in a short time, and it has achieved a longer median overall survival and disease-free survival time compared with sequential TACE and PVE or PVE-only for patients with large hepatocellular carcinoma before major hepatectomy.