Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2020; 26(28): 3998-4017
Published online Jul 28, 2020. doi: 10.3748/wjg.v26.i28.3998
Secondary causes of inflammatory bowel diseases
Yezaz A Ghouri, Veysel Tahan, Bo Shen
Yezaz A Ghouri, Veysel Tahan, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Missouri- School of Medicine, Columbia, MO 65201, United States
Bo Shen, Department of Medicine and Surgery, Interventional IBD Center, Columbia University Irving Medical Center/New York Presbyterian Hospital, New York, NY 10032, United States
Author contributions: Ghouri YA review of scientific literature, writing of the manuscript and designing the table; Tahan V review of scientific literature and editing of the manuscript; Shen B review of scientific literature and editing of the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Bo Shen, MD, Professor of the Edelman-Jarislowsky Surgical Sciences, Medicine and Surgical Sciences, Columbia University Irving Medical Center/New York Presbyterian Hospital, 161 Ft Washington Avenue, Herbert Irving Pavilion Rm 843, New York, NY 10032, United States.
Received: April 8, 2020
Peer-review started: April 8, 2020
First decision: April 30, 2020
Revised: May 15, 2020
Accepted: July 16, 2020
Article in press: July 16, 2020
Published online: July 28, 2020
Core Tip

Core tip: Inflammatory bowel diseases (IBD) are chronic illnesses of the gastrointestinal tract with no clearly defined etiology and are traditionally termed as primary IBD. It is generally believed that IBD results from abnormal immune response to dysbiosis of gut microbiota in a genetically susceptible individual. IBD or IBD-like conditions may also be caused by well-defined etiologies; such as medical, surgical, and organ transplantation. These conditions are coined as secondary IBD. In this review we attempted to highlight some etiological factors, pathogenetic pathways, and clinical features of secondary IBD.