Li H, Lyu W. Intestinal NK/T cell lymphoma: A case report. World J Gastroenterol 2020; 26(27): 3989-3997 [PMID: 32774072 DOI: 10.3748/wjg.v26.i27.3989]
Corresponding Author of This Article
Wen Lyu, MD, Chief Doctor, Director, Department of Gastroenterology, Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 4, Xueshi Road, Shangcheng District, Hangzhou 310000, Zhejiang Province, China. lihui-cy@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jul 21, 2020; 26(27): 3989-3997 Published online Jul 21, 2020. doi: 10.3748/wjg.v26.i27.3989
Intestinal NK/T cell lymphoma: A case report
Hui Li, Wen Lyu
Hui Li, Wen Lyu, Department of Gastroenterology, Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Author contributions: Li H and Lyu W designed this case report; Lyu W performed the endoscopy examination; Li H followed the patient, recorded her medical information, and wrote the paper.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wen Lyu, MD, Chief Doctor, Director, Department of Gastroenterology, Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 4, Xueshi Road, Shangcheng District, Hangzhou 310000, Zhejiang Province, China. lihui-cy@163.com
Received: March 31, 2020 Peer-review started: March 31, 2020 First decision: April 29, 2020 Revised: June 9, 2020 Accepted: June 23, 2020 Article in press: June 23, 2020 Published online: July 21, 2020 Processing time: 112 Days and 7.8 Hours
Core Tip
Core tip: The incidence of intestinal NK/T cell lymphoma (NKTCL) is extremely low, and the clinical symptoms are atypical. The misdiagnosis rate is high, and the patient's prognosis is poor. It is commonly caused by Epstein-Barr virus infection. At present, the etiology of this disease is unclear. The patient in this case was eventually diagnosed with intestinal NKTCL. The patient’s condition did not improve after treatment with hormones and infliximab, and she eventually died. This case reminds us that more potential molecular markers need to be explored. The molecular regulatory network needs to be supplemented to help with the differential diagnosis. Clinicians and pathologists need to improve their awareness of this disease and reduce the rate of misdiagnosis.
