Meta-Analysis
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 7, 2019; 25(37): 5711-5731
Published online Oct 7, 2019. doi: 10.3748/wjg.v25.i37.5711
Is total laparoscopic pancreaticoduodenectomy superior to open procedure? A meta-analysis
Hua Zhang, Xiang Lan, Bing Peng, Bo Li
Hua Zhang, Xiang Lan, Bo Li, Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Bing Peng, Department of Pancreatic Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Zhang H, Lan X, Peng B, and Li B designed the research; Zhang H, Lan X, and Peng B performed the research and acquired the data; Zhang H, Lan X, and Li B analyzed and interpreted the data; Zhang H and Lan X drafted the article; Peng B and Li B proofread and revised the manuscript.
Conflict-of-interest statement: There is no conflict of interest associated with any of authors in this manuscript.
PRISMA 2009 Checklist statement: We have read the PRISMA 2009 checklist, and the manuscript was prepared and revised in accordance with the PRISMA 2009 checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bo Li, MD, PhD, Professor, Surgeon, Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, 37 Guoxue Road, Wuhou District, Chengdu 610041, Sichuan Province, China. libohuaxi@163.com
Telephone: +86-18980601470 Fax: +86-28-85423724
Received: April 15, 2019
Peer-review started: April 15, 2019
First decision: June 16, 2019
Revised: July 10, 2019
Accepted: August 7, 2019
Article in press: August 7, 2019
Published online: October 7, 2019
Processing time: 169 Days and 13.5 Hours
Core Tip

Core tip: This is a meta-analysis with the largest number of cases so far comparing total laparoscopic pancreaticoduodenectomy (TLPD) and open pancreaticoduodenectomy (OPD). In recent years, the reports or comparisions between TLPD and OPD are increasing, but most of them have a very small number of cases included, and the quality and reliability are limited. In this meta-analysis, we reviewed the published literature on this topic until now with the largest number of cases, thus the conclusion is much more reliable. In addition, our study analyzed the effects of laparoscopic skills not only on intraoperative parameters and postoperative complications, but also on oncological outcomes to ensure its safety and feasibility.