Systematic Reviews
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2019; 25(31): 4534-4554
Published online Aug 21, 2019. doi: 10.3748/wjg.v25.i31.4534
Small bowel capsule endoscopy and treat-to-target in Crohn's disease: A systematic review
Catherine Le Berre, Caroline Trang-Poisson, Arnaud Bourreille
Catherine Le Berre, Caroline Trang-Poisson, Arnaud Bourreille, Institut des Maladies de l’Appareil Digestif, Nantes University Hospital, Nantes 44093, France
Author contributions: Le Berre C and Bourreille A designed and performed the literature review and carried out the analysis; Le Berre C drafted the initial manuscript; Bourreille A and Trang-Poisson C critically revised the manuscript for important intellectual content; All authors have read and approved the final version to be published.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA Checklist (2009), and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Arnaud Bourreille, MD, PhD, Professor, Institut des Maladies de l’Appareil Digestif, Nantes University Hospital, 1 place Alexis Ricordeau, Nantes 44093, France. arnaud.bourreille@chu-nantes.fr
Telephone: +33-2-40083152 Fax: +33-2-40083154
Received: March 26, 2019
Peer-review started: March 26, 2019
First decision: April 11, 2019
Revised: May 28, 2019
Accepted: July 19, 2019
Article in press: July 19, 2019
Published online: August 21, 2019
Core Tip

Core tip: The treatment goal in patients with Crohn’s disease (CD) combines both clinical and endoscopic remission. Assessment of the small bowel (SB) is substantial because it may have a significant impact on prognosis. Small bowel capsule endoscopy (SBCE) allows direct visualization of the entire SB mucosal surface. We conducted a systematic literature review that aimed to provide a global overview of the studies that assessed the use of SBCE in a treat-to-target strategy in patients with CD. SBCE could be useful for refining the disease location, assessing mucosal healing in patients receiving treatment, and monitoring patients in the post-operative setting.