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World J Gastroenterol. Aug 14, 2019; 25(30): 4181-4198
Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4181
Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models in vivo
Hilda Vargas-Robles, Karla Fabiola Castro-Ochoa, Alí Francisco Citalán-Madrid, Michael Schnoor
Hilda Vargas-Robles, Karla Fabiola Castro-Ochoa, Alí Francisco Citalán-Madrid, Michael Schnoor, Department for Molecular Biomedicine, Cinvestav-IPN, Mexico City 07360, Mexico
Author contributions: All authors reviewed the literature, wrote the paper, and approved the final version; Schnoor M was responsible for the conceptual design of this review.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors who contributed to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Michael Schnoor, PhD, Professor, Department for Molecular Biomedicine, Cinvestav-IPN, San Pedro Zacatenco, GAM, Mexico City 07360, Mexico. mschnoor@cinvestav.mx
Telephone: +52-55-5747-3321
Received: April 30, 2019
Peer-review started: April 30, 2019
First decision: May 30, 2019
Revised: June 12, 2019
Accepted: July 5, 2019
Article in press: July 5, 2019
Published online: August 14, 2019
Core Tip

Core tip: This review summarizes current knowledge on how nutritional supplements with anti-inflammatory and antioxidative properties such as vitamins, fatty acids and phytochemicals contribute to intestinal epithelial junction stabilization and maintenance of barrier integrity during experimental colitis.