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Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2019; 25(21): 2565-2580
Published online Jun 7, 2019. doi: 10.3748/wjg.v25.i21.2565
Colorectal cancer screening from 45 years of age: Thesis, antithesis and synthesis
Alessandro Mannucci, Raffaella Alessia Zuppardo, Riccardo Rosati, Milena Di Leo, José Perea, Giulia Martina Cavestro
Alessandro Mannucci, Raffaella Alessia Zuppardo, Giulia Martina Cavestro, Gastroenterology and Gastrointestinal Endoscopy Unit, Division of Experimental Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy
Riccardo Rosati, Department of Surgery, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy
Milena Di Leo, Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Research Hospital, Department of Biomedical Science, Humanitas University, Milan 20090, Italy
José Perea, Surgery Department, “Fundación Jiménez Díaz” University Hospital, Madrid 28040, Spain
José Perea, Health Research Institute-Fundación Jiménez Díaz University Hospital, Madrid 28040, Spain
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: All authors declare they have no potential competing conflicts of interest and no financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Giulia Martina Cavestro, MD, PhD, Associate Professor, Gastroenterology and Gastrointestinal Endoscopy Unit, Division of Experimental Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milano 20132, Italy. cavestro.giuliamartina@unisr.it
Telephone: +39-2-26435508
Received: March 11, 2019
Peer-review started: March 11, 2019
First decision: April 4, 2019
Revised: April 15, 2019
Accepted: April 19, 2019
Article in press: April 20, 2019
Published online: June 7, 2019
Processing time: 89 Days and 14.5 Hours
Core Tip

Core tip: Colorectal cancer is a significant public health threat to individuals younger than 50 years of age, but they currently do not receive any screening. We discuss the advantages and disadvantages of screening from 45 years of age.