Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2019; 25(2): 245-257
Published online Jan 14, 2019. doi: 10.3748/wjg.v25.i2.245
Published online Jan 14, 2019. doi: 10.3748/wjg.v25.i2.245
Submucosal tunneling endoscopic resection: An effective and safe therapy for upper gastrointestinal submucosal tumors originating from the muscularis propria layer
Chen Du, Ning-Li Chai, En-Qiang Ling-Hu, Zhen-Juan Li, Long-Song Li, Jia-Le Zou, Lei Jiang, Zhong-Sheng Lu, Jiang-Yun Meng, Ping Tang, Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Du C, Chai NL, and Ling-Hu EQ designed the study; Chai NL, Ling-Hu EQ, Lu ZS, Meng JY, and Tang P performed the research; Du C, Li ZJ, Li LS, Zou JL, and Jiang L contributed new reagents or analytic tools; Du C and Li ZJ analysed the data; Du C wrote the paper; Chai NL and Ling-Hu EQ made critical revisions to the article for important intellectual content; all authors approved the final article; Du C and Chai NL contributed equally to this manuscript.
Supported by the National Program on Key Research Project (13-5 Program) , No. 2016YFC1303601 ; and Chinese PLA General Hospital Clinical Research , No. 2012FC-TSYS-3035 .
Institutional review board statement: The clinical trial of this paper was reviewed and approved by the Committee of Medical Ethics of Chinese PLA General Hospital.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrolment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: En-Qiang Ling-Hu, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Telephone: +86-10-68182255 Fax: +86-10-68154653
Received: September 27, 2018
Peer-review started: September 27, 2018
First decision: October 23, 2018
Revised: November 19, 2018
Accepted: December 19, 2018
Article in press: December 19, 2018
Published online: January 14, 2019
Processing time: 110 Days and 5.4 Hours
Peer-review started: September 27, 2018
First decision: October 23, 2018
Revised: November 19, 2018
Accepted: December 19, 2018
Article in press: December 19, 2018
Published online: January 14, 2019
Processing time: 110 Days and 5.4 Hours
Core Tip
Core tip: Submucosal tunneling endoscopic resection (STER) was initially reported in 2012 for the resection of submucosal tumors (SMTs) originating from the muscularis propria. It has an advantage in maintaining the integrity of the mucosa. Several studies have demonstrated the effectiveness and safety of STER; however; few studies have enrolled large populations over 100 cases and compared the effectiveness and safety of STER for SMTs located in different locations. In this study, we aimed to further evaluate the effectiveness and safety of STER for gastrointestinal SMTs in a large population and compare the feasibility of STER for resection of esophageal and cardial SMTs.