Copyright
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 21, 2018; 24(7): 862-869
Published online Feb 21, 2018. doi: 10.3748/wjg.v24.i7.862
Published online Feb 21, 2018. doi: 10.3748/wjg.v24.i7.862
Predictors of post-treatment stenosis in cervical esophageal cancer undergoing high-dose radiotherapy
Jun Won Kim, Tae Hyung Kim, Ik Jae Lee, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, South Korea
Jie-Hyun Kim, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, South Korea
Author contributions: All authors helped to perform the research; Kim JW contributed to manuscript writing, data analysis and drafting design; Kim TH contributed to data analysis; Kim JH contributed to performing procedures; and Lee IJ contributed to drafting concept and design and performing procedures.
Supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, No. 2017R1D1A1B03035047; and the National Research Foundation of Korea Grant funded by the Korean Government, No. NRF-2017M2A2A4A03083634.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Gangnam Severance Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ik Jae Lee, MD, PhD, Associate Professor, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, South Korea. ikjae412@yuhs.ac
Telephone: +82-2-20193158 Fax: +82-2-20194855
Received: December 11, 2017
Peer-review started: December 11, 2017
First decision: December 20, 2017
Revised: December 25, 2017
Accepted: January 16, 2018
Article in press: January 16, 2018
Published online: February 21, 2018
Peer-review started: December 11, 2017
First decision: December 20, 2017
Revised: December 25, 2017
Accepted: January 16, 2018
Article in press: January 16, 2018
Published online: February 21, 2018
Core Tip
Core tip: This study reports the outcome and toxicity of high dose (median 63 Gy) radiotherapy for cervical esophageal cancer. Post-RT stenosis and tracheoesophageal fistula rates were 26% and 6.5%, respectively. Stenosis at diagnosis and post-RT stenosis/fistula was significantly associated with overall survival. Complete circumference involvement was significantly associated with post-RT stenosis but dose higher than 60 Gy was not.